Proposed case of mesalazine-induced cardiomyopathy in severe ulcerative colitis.

Abstract

Five-amino salicylic acids are recommended for use in the management of inflammatory bowel disease, cardiac complications are a rare although recognised phenomenon. This report aims to highlight this serious but rare adverse reaction. We report here a case of a young man presenting with cardiogenic shock in the context of recent mesalazine treatment in severe ulcerative colitis.

• Authors: Kathryn Fleming, Andrew Ashcroft, Christopher Alexakis, Demitrios Tzias, Christopher Groves, Andrew Poullis
• Journal: World journal of gastroenterology (World J Gastroenterol) Vol. 21 Issue 11 Pg. 3376-9 (Mar 21 2015) ISSN: 2219-2840 [Electronic] United States
• PMID: 25805947 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Mesalamine

Topics

• Adult
• Anti-Inflammatory Agents, Non-Steroidal (adverse effects)
• Cardiomyopathies (chemically induced, diagnosis, therapy)
• Colitis, Ulcerative (diagnosis, drug therapy)
• Drug Substitution
• Humans
• Magnetic Resonance Imaging
• Male
• Mesalamine (adverse effects)
• Severity of Illness Index
• Shock, Cardiogenic (chemically induced)
• Treatment Outcome