Generation mechanism of hydroxyl radical species and its lifetime prediction during the plasma-initiated ultraviolet (UV) photolysis.

Abstract

Through this work, we have elucidated the mechanism of hydroxyl radicals (OH(•)) generation and its life time measurements in biosolution. We observed that plasma-initiated ultraviolet (UV) photolysis were responsible for the continues generation of OH(•) species, that resulted in OH(•) to be major reactive species (RS) in the solution. The density and lifetime of OH(•) species acted inversely proportional to each other with increasing depth inside the solution. The cause of increased lifetime of OH(•) inside the solution is predicted using theoretical and semiempirical calculations. Further, to predict the mechanism of conversion of hydroxide ion (OH(-)) to OH(•) or H2O2 (hydrogen peroxide) and electron, we determined the current inside the solution of different pH. Additionally, we have investigated the critical criterion for OH(•) interaction on cancer cell inducing apoptosis under effective OH(•) exposure time. These studies are innovative in the field of plasma chemistry and medicine.

• Authors: Pankaj Attri, Yong Hee Kim, Dae Hoon Park, Ji Hoon Park, Young J Hong, Han Sup Uhm, Kyoung-Nam Kim, Alexander Fridman, Eun Ha Choi
• Journal: Scientific reports (Sci Rep) Vol. 5 Pg. 9332 (Mar 20 2015) ISSN: 2045-2322 [Electronic] England
• PMID: 25790968 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Plasma Gases
• Hydroxyl Radical
• Hydrogen Peroxide

Topics

• Hydrogen Peroxide (chemistry)
• Hydroxyl Radical (chemistry)
• Photolysis
• Plasma Gases
• Ultraviolet Rays