Chemical constituents and bioactivities of Panax ginseng (C. A. Mey.).

Abstract

Ginseng, Panax ginseng (C. A. Mey.), is a well-known Chinese traditional medicine in the Far East and has gained popularity in the West during the last decade. There is extensive literature on the chemical constituents and bioactivities of ginseng. In this paper we compiled the chemical constituents isolated and detected from ginseng including polysaccharides, ginsenosides, peptides, polyacetylenic alcohols, fatty acids, etc. Meanwhile we summarized the biological activities of ginseng, which have been reported over the past few decades, including: anti-aging activity, anti-diabetic activity, immunoregulatory activity, anti-cancer activity, neuroregulation activity, wound and ulcer healing activity, etc. Nevertheless, further studies to exploit other kinds of constituents and new biological activities of ginseng are still necessary to facilitate research and development in the future.

• Authors: Wenwen Ru, Dongliang Wang, Yunpeng Xu, Xianxian He, Yang-En Sun, Liyan Qian, Xiangshan Zhou, Yufeng Qin
• Journal: Drug discoveries & therapeutics (Drug Discov Ther) Vol. 9 Issue 1 Pg. 23-32 (Feb 2015) ISSN: 1881-7831 [Print] Japan
• PMID: 25788049 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Antineoplastic Agents
• Fibrinolytic Agents
• Immunologic Factors
• Plant Extracts

Topics

• Aging (drug effects)
• Animals
• Antineoplastic Agents (pharmacology)
• Fibrinolytic Agents (pharmacology)
• Humans
• Immunologic Factors (pharmacology)
• Panax (chemistry)
• Plant Extracts (pharmacology)