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Infected cells call their killers to the scene of the crime.

Abstract
Effector CD8(+) T cells scan tissues to locate and kill infected host cells. In this issue of Immunity, Hickman et al. (2015) show that the exploration is not random: infected monocytes attract their assassins by secreting chemokines, which accelerates clearance of epicutaneous vaccinia virus infection.
AuthorsLalit K Beura, David Masopust
JournalImmunity (Immunity) Vol. 42 Issue 3 Pg. 399-401 (Mar 17 2015) ISSN: 1097-4180 [Electronic] United States
PMID25786170 (Publication Type: Comment, Journal Article)
CopyrightCopyright © 2015 Elsevier Inc. All rights reserved.
Chemical References
  • Cxcr3 protein, mouse
  • Receptors, CXCR3
Topics
  • Animals
  • Female
  • Humans
  • Keratinocytes (immunology)
  • Poxviridae Infections (immunology)
  • Receptors, CXCR3 (immunology)
  • Skin (immunology)
  • T-Lymphocytes, Cytotoxic (immunology)
  • Vaccinia virus (immunology)

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