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Nootropic effect of meadowsweet (Filipendula vulgaris) extracts.

Abstract
The effects of the extracts of the aboveground parts of Filipendula vulgaris Moench on the behavior and memory of mice after hypoxic injury and their physical performance in the open-field test were studied using the models of hypoxia in a sealed volume, conditioned passive avoidance response (CPAR), and forced swimming with a load. The extracts improved animal resistance to hypoxia, normalized orientation and exploration activities, promoted CPAR retention after hypoxic injury, and increased physical performance. Aqueous extract of meadowsweet had the most pronounced effect that corresponded to the effect of the reference drug piracetam. These effects were probably caused by modulation of hippocampal activity.
AuthorsI V Shilova, N I Suslov
JournalBulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 158 Issue 5 Pg. 659-63 (Mar 2015) ISSN: 1573-8221 [Electronic] United States
PMID25778665 (Publication Type: Journal Article)

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