Abstract | AIMS:
Obesity is associated with increased cardiovascular (CV) morbidity and mortality. Weight loss improves several risk factors for CV diseases, but anti- obesity medications and lifestyle interventions have failed to modify primary CV endpoints. This paper reviews bariatric surgery in prevention of CV diseases and CV mortality, and analyzes the possible mechanisms involved. DATA SYNTHESIS: CONCLUSIONS: Reduction of CV diseases is mediated by the pleiotropic effects of weight loss through surgery. Available data do not allow conclusions on the comparative efficacy of different surgical techniques; the choice of the surgical technique for a single patient remains an open question, and it is likely that the degree of prevention of CV diseases depends, among other factors, on the baseline conditions of patients. Large prospective studies are needed to address this issue in morbidly obese patients.
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Authors | A Boido, V Ceriani, F Cetta, F Lombardi, A E Pontiroli |
Journal | Nutrition, metabolism, and cardiovascular diseases : NMCD
(Nutr Metab Cardiovasc Dis)
Vol. 25
Issue 5
Pg. 437-43
(May 2015)
ISSN: 1590-3729 [Electronic] Netherlands |
PMID | 25770762
(Publication Type: Comparative Study, Journal Article, Review)
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Copyright | Copyright © 2015 Elsevier B.V. All rights reserved. |
Topics |
- Bariatric Surgery
(adverse effects)
- Cardiovascular Diseases
(epidemiology, mortality, prevention & control)
- Comorbidity
- Evidence-Based Medicine
- Gastrectomy
(adverse effects)
- Gastric Bypass
(adverse effects)
- Gastroplasty
(adverse effects)
- Humans
- Obesity, Morbid
(epidemiology, surgery)
- Precision Medicine
- Weight Loss
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