Primary myxoid liposarcoma of the ovary in a postpartum female: a case report and review of literature.

Abstract

A 36-year-old gravida 4, para 2 African-American woman, presented at three months postpartum with a right ovarian mass identified on a lumbar spine MRI as part of a neurology workup for persistent lower back pain. A follow-up pelvic ultrasound noted a 7.0 × 6.1 × 3.8 cm septated mixed cystic and solid mass. Exploratory laparoscopy and right ovarian cystectomy yielded a final pathologic diagnosis of intermediate grade myxoid liposarcoma, confirmed with DDIT3 gene rearrangement studies.

• Authors: Sharon X Liang, Brooke Howitt, Matthew J Blitz, Tamfiqul Bhuiya, Farnaz Thamasebi, Jason Sternchos, Karin Shih
• Journal: International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists (Int J Gynecol Pathol) Vol. 34 Issue 3 Pg. 298-302 (May 2015) ISSN: 1538-7151 [Electronic] United States
• PMID: 25760901 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• DDIT3 protein, human
• Transcription Factor CHOP

Topics

• Adult
• Female
• Humans
• In Situ Hybridization, Fluorescence
• Liposarcoma, Myxoid (genetics, pathology)
• Ovarian Neoplasms (genetics, pathology)
• Postpartum Period
• Transcription Factor CHOP (genetics)