Treatment of acquired and small congenital melanocytic nevi with combined Er: YAG laser and long-pulsed alexandrite laser in Asian skin.

There is no gold standard for the treatment of benign melanocytic nevi for cosmetic purposes.
To investigate the efficacy and safety of combined treatment with the short-pulsed erbium:yttrium-aluminum-garnet (Er:YAG) and long-pulsed alexandrite laser for acquired melanocytic nevi (AMN) and small congenital melanocytic nevi (CMN).
Fifty-eight AMN and 7 small CMN in 24 Korean patients were treated with Er:YAG laser followed by long-pulsed alexandrite laser at 1-month intervals.
At 8 weeks after the final treatment, all treated nevi showed complete removal of pigmentation, and the mean overall improvement score assessed by physicians, with a quartile grading scale, was 3.6 ± 0.7. The mean number of treatment sessions required to treat CMN (1.5 ± 0.3) was significantly greater than that for junctional (1.1 ± 0.2) or compound (1.2 ± 0.5) AMN. Postinflammatory hyperpigmentation (4.6%), erythema (9.2%), hypertrophic scars (1.5%), and mild atrophic scars (10.8%) were observed, but all resolved within 6 months, except for hypertrophic scars and 1 atrophic scar. Recurrence of pigmentation was observed in 1 CMN (1.5%) during 6 months of follow-up.
Combined treatment with Er:YAG laser and long-pulsed alexandrite laser is effective for the removal of small benign melanocytic nevi with minimal adverse effects and low recurrence rates.
AuthorsSang Eun Lee, Ji Young Choi, Kyung Tai Hong, Kyung Real Lee
JournalDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] (Dermatol Surg) Vol. 41 Issue 4 Pg. 473-80 (Apr 2015) ISSN: 1524-4725 [Electronic] United States
PMID25760556 (Publication Type: Journal Article)
  • Adolescent
  • Adult
  • Child
  • Dermoscopy
  • Female
  • Follow-Up Studies
  • Humans
  • Laser Therapy (methods)
  • Lasers, Solid-State (therapeutic use)
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Nevus, Pigmented (congenital, pathology, surgery)
  • Prospective Studies
  • Republic of Korea
  • Skin Neoplasms (congenital, pathology, surgery)
  • Treatment Outcome
  • Young Adult

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