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[Evaluation of the efficacy of the magnesium salt of N-acetyl-aspartyl-glutamic acid in the treatment of acute rhinitis].

Abstract
The object of the above study was to evaluate the tolerability and possible therapeutic use of MgNAAGA (Mg salt of N-acetyl-aspartyl-glutamic acid) in patients with allergic rhinitis. Out of 22 subjects with respiratory allergy, 12 were treated for 15 days with MgNAAGA and 10 with DSCG for the same length of time. During this period, patients kept a diary in which they recorded the following symptoms: rhinorrhea, itching, sneezing and nasal obstruction. The trial drug was found to be well tolerated and not to give rise to relevant side effects. The therapeutic efficacy was similar to that of DSCG.
AuthorsA Miadonna, A Tedeschi, P Parravicini, M Lorini
JournalLa Clinica terapeutica (Clin Ter) Vol. 131 Issue 3 Pg. 173-6 (Nov 15 1989) ISSN: 0009-9074 [Print] Italy
Vernacular TitleValutazione dell'efficacia del sale di Mg dell'acido N-acetil-aspartil-glutammico (Mg NAAGA) nel trattamento della rinite acuta.
PMID2575479 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Dipeptides
  • Histamine H1 Antagonists
  • isospaglumic acid
  • Cromolyn Sodium
Topics
  • Administration, Intranasal
  • Adolescent
  • Adult
  • Cromolyn Sodium (therapeutic use)
  • Dipeptides (administration & dosage, therapeutic use)
  • Drug Evaluation
  • Histamine H1 Antagonists (administration & dosage, therapeutic use)
  • Humans
  • Rhinitis, Allergic, Perennial (drug therapy)
  • Rhinitis, Allergic, Seasonal (drug therapy)

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