[Research progress on pharmacology, pharmacokinetics and determination of ergosta-4,6,8 (14),22-tetraen-3-one].

Abstract

Ergosta-4,6,8(14),22-tetraen-3-one (ergone) is one of main components in many medicinal fungi. Ergone has been reported to possess the activities of diuresis, cytotoxicity, antitumor, immunosuppression, as well as treatment of chronic kidney disease. According to reported literatures, an overview of spectroscopy characteristics, content determination, pharmacological activity and pharmacokinetics, etc. for ergone is presented in this review. Furthermore, the present review can provide a certain reference value for the further study and development of ergone.

• Authors: Han Chen, Dan-Qian Chen, Quan-Fu Li, Peng-Fei Li, Hua Chen, Ying-Yong Zhao
• Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (Zhongguo Zhong Yao Za Zhi) Vol. 39 Issue 20 Pg. 3905-9 (Oct 2014) ISSN: 1001-5302 [Print] China
• PMID: 25751937 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Cholestenones
• Drugs, Chinese Herbal
• ergosta-4,6,8(14),22-tetraen-3-one

Topics

• Animals
• Cholestenones (chemistry, pharmacokinetics, pharmacology)
• Drugs, Chinese Herbal (chemistry, pharmacokinetics, pharmacology)
• Humans