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Determination of para-arsanilic acid with improved diazotization reaction using differential pulse cathodic stripping voltammetry in aqueous system.

Abstract
Para-arsanilic acid (p-ASA) has been widely used in the poultry industry to promote growth and prevent dysentery. It is excreted unchanged in the manure and released into non-target sites causing organoarsenic pollution risk to the environment and living system. Therefore, simple and effective analytical strategies are demanded for determining the samples that contain p-ASA. However, direct determination of both p-ASA and ortho-arsanilic acid (o-ASA) using differential pulse cathodic stripping voltammetry (DPCSV) gives the similar voltammograms that directly hamper the analysis used by the DPCSV technique. In this study, a method to determine and differentiate p-ASA from o-ASA via diazotization and coupling reaction of the amine groups followed by the direct DPCSV determination of diazo compounds is presented. The diazotization reaction carried out at pH 1.5 and 0 ± 1°C for 10 min showed two reduction peaks in DPCSV at-70 mV and -440 mV vs. Ag/AgCl (KCl 3 M). However, when the diazotization reaction was performed at pH 12.5 and 0 ± 1°C for 40 min, a coloured azo compound was produced and the DPCSV showed only one reduction peak that appeared at -600 mV vs. Ag/AgCl (3 M of KCl). The results of this study show that only p-ASA compound gave a reduction peak, whereas o-ASA compound did not give any peak. The detection limit of p-ASA was found to be 4 × 10(-8 )M. As a result, the proposed electro-analytical technique might be a good candidate to determine and differentiate the p-ASA present in the poultry and environmental samples.
AuthorsMarpongahtun Misni, Palanivel Sathishkumar, Rahmalan Ahamad, Abdull Rahim MohdYusoff
JournalEnvironmental technology (Environ Technol) Vol. 36 Issue 17 Pg. 2249-54 ( 2015) ISSN: 1479-487X [Electronic] England
PMID25749108 (Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Azo Compounds
  • Water Pollutants, Chemical
  • Water
  • Arsanilic Acid
Topics
  • Animal Feed (analysis)
  • Arsanilic Acid (analysis)
  • Azo Compounds (analysis)
  • Electrochemical Techniques (methods)
  • Electrodes
  • Limit of Detection
  • Water (analysis)
  • Water Pollutants, Chemical (analysis)

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