Terbium doped SnO2 nanoparticles as white emitters and SnO2:5Tb/Fe3O4 magnetic luminescent nanohybrids for hyperthermia application and biocompatibility with HeLa cancer cells.

Abstract

SnO2:5Tb (SnO2 doped with 5 at% Tb(3+)) nanoparticles were synthesised by a polyol method and their luminescence properties at different annealing temperatures were studied. Characterization of nanomaterials was done by X-ray diffraction (XRD), Fourier transformation infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and vibrating sample magnetometry (VSM). XRD studies indicate that the prepared nanoparticles were of tetragonal structures. Upon Tb(3+) ion incorporation into SnO2, Sn(4+) changes to Sn(2+) and, on annealing again at higher temperature, Sn(2+) changes to Sn(4+). The prepared nanoparticles were spherical in shape. Sn-O vibrations were found from the FTIR studies. In photoluminescence studies, the intensity of the emission peaks of Tb(3+) ions increases with the increase of annealing temperature, and emission spectra lie in the region of white emission in the CIE diagram. CCT calculations show that the SnO2:5Tb emission lies in cold white emission. Quantum yields up to 38% can be obtained for 900 °C annealed samples. SnO2:5Tb nanoparticles were well incorporated into the PVA polymer and such a material incorporated into the polymer can be used for display devices. The SnO2:5Tb/Fe3O4 nanohybrid was prepared and investigated for hyperthermia applications at different concentrations of the nanohybrid. This achieves a hyperthermia temperature (42 °C) under an AC magnetic field. The hybrid nanomaterial SnO2:5Tb/Fe3O4 was found to exhibit biocompatibility with HeLa cells (human cervical cancer cells) at concentrations up to 74% for 100 μg L(-1). Also, this nanohybrid shows green emission and thus it will be helpful in tracing magnetic nanoparticles through optical imaging in vivo and in vitro application.

• Authors: Laishram Priyobarta Singh, Ningthoujam Premananda Singh, Sri Krishna Srivastava
• Journal: Dalton transactions (Cambridge, England : 2003) (Dalton Trans) Vol. 44 Issue 14 Pg. 6457-65 (Apr 14 2015) ISSN: 1477-9234 [Electronic] England
• PMID: 25747103 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Biocompatible Materials
• Luminescent Agents
• Tin Compounds
• Water
• Terbium
• Ethylene Glycol
• stannic oxide
• Ferrosoferric Oxide

Topics

• Biocompatible Materials (chemistry, pharmacology)
• Cell Survival (drug effects)
• Ethylene Glycol (chemistry)
• Ferrosoferric Oxide (chemistry)
• HeLa Cells
• Humans
• Luminescent Agents (chemistry, pharmacology)
• Magnetic Phenomena
• Nanoparticles (chemistry)
• Temperature
• Terbium (chemistry)
• Tin Compounds (chemistry)
• Water (chemistry)