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Exacerbation of adenomyosis symptomatology by estrogen-progestin therapy: a case report and histopathological observations.

Abstract
The present case report illustrates the hormonal sensitivity of adenomyosis. Administration of an estrogen-progestin combination for what was felt to be symptomatic endometriosis resulted in exacerbation of symptoms and growth of adenomyomas. Histopathologic examination of the hysterectomy specimen revealed a pattern of decidualization previously unreported, but consistent with current theories of experimental in vivo and in vitro decidua formation.
AuthorsR J Falk, B R Mullin
JournalInternational journal of fertility (Int J Fertil) 1989 Nov-Dec Vol. 34 Issue 6 Pg. 386-9 ISSN: 0020-725X [Print] United States
PMID2574708 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Contraceptives, Oral, Combined
  • Ethynodiol Diacetate
  • Bisecurin I
  • Mestranol
Topics
  • Adult
  • Contraceptives, Oral, Combined (adverse effects)
  • Endometriosis (chemically induced, pathology)
  • Ethynodiol Diacetate (adverse effects)
  • Female
  • Humans
  • Leiomyoma (chemically induced, pathology)
  • Mestranol (adverse effects)
  • Neoplasms, Multiple Primary (chemically induced, pathology)
  • Uterine Neoplasms (chemically induced, pathology)
  • Uterus (pathology)

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