Abstract | BACKGROUND: AIM: METHODS: 105 patients undergoing intrathecal anesthesia for elective cesarean delivery were randomized and allocated to receive a preload of 500 ml HES 130/0.4 (HES Group) or a preload of 1500 ml 9‰ saline solution (CR group). Blood pressure and heart rate were recorded at baseline and after spinal anesthesia (every minute for the first 10 min, every 3 min for the next 10 min, and then every 5 min for the last 20 min). The primary outcome was to compare the incidence of hypotension (defined as a 20% reduction in systolic arterial pressure from baseline) between the two preloading regimens. Vasopressor requirements (i.v. bolus of 6 mg ephedrine) were also compared. RESULTS: The incidence of hypotension was 87% in the CR group and 69% in the HES group (p= 0.028). Ephedrine requirement, incidence of nausea, and/or vomiting and neonatal outcome did not significantly differ between the two groups. CONCLUSION:
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Authors | Chihebeddine Romdhani, Walid Trabelsi, Anis Lebbi, I Naas, Haythem Elaskri, Hedi Gharsallah, Radhouane Rachdi, Mustapha Ferjani |
Journal | La Tunisie medicale
(Tunis Med)
Vol. 92
Issue 6
Pg. 406-10
(Jun 2014)
ISSN: 0041-4131 [Print] Tunisia |
PMID | 25741842
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Hydroxyethyl Starch Derivatives
- Sodium Chloride
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Topics |
- Adult
- Anesthesia, Obstetrical
(adverse effects)
- Anesthesia, Spinal
(adverse effects)
- Cesarean Section
- Female
- Humans
- Hydroxyethyl Starch Derivatives
(administration & dosage)
- Hypotension
(epidemiology, etiology, prevention & control)
- Incidence
- Pregnancy
- Prospective Studies
- Sodium Chloride
(administration & dosage)
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