[A case of recurrent sigmoid colon cancer with multiple peritoneal and liver metastases controlled effectively by resection].

Abstract

A 71 year -old man underwent sigmoid colectomy for sigmoid colon cancer. A solitary liver metastasis found on examination 8 months after the initial surgery was resected. One year after the second surgery, 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) and computed tomography (CT) revealed multiple peritoneal and liver metastases, and laparotomy was performed. All metastatic lesions were resectable or controllable. Eight peritoneal and 3 hepatic lesions were removed surgically and 1 hepatic lesion was treated with radiofrequency ablation. Eight months after the third surgery FDGPET and CT examination again revealed recurrence of liver and peritoneal metastases. Chemotherapy was ineffective and metastases progressed and resulted in death 26 months after the third surgery (39 months after the initial recurrence). We suggest that aggressive resection for multiple peritoneal and liver metastases can be an effective therapy for selected patients with recurrent colon cancer.

• Authors: Nariatsu Sato, Hideyo Mukubo, Shinichi Nakanuma, Toshiaki Yasui, Ichiro Kita
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 41 Issue 12 Pg. 1698-700 (Nov 2014) ISSN: 0385-0684 [Print] Japan
• PMID: 25731300 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Aged
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Fatal Outcome
• Humans
• Liver Neoplasms (drug therapy, secondary, surgery)
• Male
• Multimodal Imaging
• Peritoneal Neoplasms (drug therapy, secondary, surgery)
• Positron-Emission Tomography
• Recurrence
• Sigmoid Neoplasms (drug therapy, pathology, surgery)
• Tomography, X-Ray Computed