[Report of a case of allergic granulomatous vasculitis (Churg-Strauss syndrome)].

Abstract

A 35 year female with a previous history of asthma came to our observation about 10 months ago. She was dyspneic, showed small nodules (2 to 5 mm) in arms, hands and legs and had radiological evidence of pulmonary granulomatosis and pleural effusion. Diagnosis was made by means of cutaneous biopsy showing a necrotic granulomatous vasculitic lesions with eosinophilic infiltration and giant cells, consistent with allergic granulomatosis of Churg-Strauss syndrome. Steroid therapy alone (prednisone 1 mg/kg/die) led to a rapid and complete clinical and humoral remission. The patient is still doing an alternate day prednisone therapy (15 mg) and is well after a 10 months follow-up.

• Authors: F Albert, E Bertani, A Carabelli, G Pavia
• Journal: Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia (G Ital Dermatol Venereol) Vol. 124 Issue 3 Pg. 115-9 (Mar 1989) ISSN: 0392-0488 [Print] Italy
• Vernacular Title: Osservazioni su di un caso di vasculite granulomatosa allergica (sindrome di Churg-Strauss).
• PMID: 2572542 (Publication Type: Case Reports, English Abstract, Journal Article)

Topics

• Adult
• Asthma (complications)
• Churg-Strauss Syndrome (complications, diagnosis, pathology)
• Diagnosis, Differential
• Eosinophilia (etiology)
• Female
• Humans
• Polyarteritis Nodosa (diagnosis)