Abstract | OBJECTIVE: DESIGN: SETTING: A teaching hospital unit with an interest in general medicine and liver disease. PATIENTS: 22 "Self confessed" alcoholics admitting to a daily alcohol intake of at least 80 g for a minimum of three weeks; 15 of the 22 self confessed alcoholics admitted to hospital for alcohol withdrawal; 68 patients with alcoholic liver disease confirmed by biopsy attending outpatient clinics and claiming to be drinking less than 50 g alcohol daily; 47 patients with non-alcoholic liver disorders confirmed by biopsy; and 38 patients with disorders other than of the liver and no evidence of excessive alcohol consumption. INTERVENTION: Serial studies performed on the 15 patients undergoing alcohol withdrawal in hospital. MAIN OUTCOME measure--Determination of relative value of techniques for detecting alcohol abuse. RESULTS: CONCLUSION: As the technique is fairly simple, sensitive, and inexpensive we suggest that it may be valuable in detecting alcohol abuse.
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Authors | A Kapur, G Wild, A Milford-Ward, D R Triger |
Journal | BMJ (Clinical research ed.)
(BMJ)
Vol. 299
Issue 6696
Pg. 427-31
(Aug 12 1989)
ISSN: 0959-8138 [Print] England |
PMID | 2571374
(Publication Type: Journal Article)
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Chemical References |
- Biomarkers
- Transferrin
- carbohydrate-deficient transferrin
- Ethanol
- gamma-Glutamyltransferase
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Topics |
- Alcoholism
(blood, diagnosis)
- Biomarkers
(analysis)
- Ethanol
(blood)
- Humans
- Isoelectric Focusing
- Sensitivity and Specificity
- Transferrin
(analysis)
- gamma-Glutamyltransferase
(metabolism)
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