[Anomalies in gastric stump emptying of patients who have undergone resections for duodenal ulcer previously treated with histamine H2 receptor antagonists].

Abstract

The problem of obstructed emptying of the gastric stump after Billroth II operations in patients previously treated with H2 receptors is discussed. Statistical comparison using the Student's "t" test revealed a significant difference (t = 2.173) between those given and not given H2-antagonists and confirmed the existence of greater postoperative hypotonia in the gastric stumps of the former group. This clinical syndrome demands careful monitoring of the hydroelectrolytic balance and possibly the use of a double naso-gastric and nasojejunal tube as a precaution to ensure the delivery of the jejunal contents to the stomach. The gastrokinetic drugs metoclopramide and domperidone are also beneficial.

• Authors: L Quaranta, D Segre, L Abbo, E Balestrino, D Clerico, I Emmolo, R Cardona, S Massimino
• Journal: Minerva chirurgica (Minerva Chir) Vol. 44 Issue 10 Pg. 1475-8 (May 31 1989) ISSN: 0026-4733 [Print] Italy
• Vernacular Title: Anomalie dello svuotamento del moncone gastrico nei pazienti gastroresecati per ulcera peptica duodenale, precedentemente trattati con farmaci antagonisti dei recettori H2 dell'istamina.
• PMID: 2570381 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Histamine H2 Antagonists
• Domperidone
• Cimetidine
• Ranitidine
• Metoclopramide

Topics

• Adult
• Aged
• Cimetidine (therapeutic use)
• Domperidone (therapeutic use)
• Duodenal Ulcer (drug therapy, surgery)
• Female
• Gastric Emptying
• Gastroenterostomy
• Histamine H2 Antagonists (therapeutic use)
• Humans
• Male
• Metoclopramide (therapeutic use)
• Middle Aged
• Postgastrectomy Syndromes (drug therapy)
• Ranitidine (therapeutic use)