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Small-bowel neuroendocrine tumor and retroperitoneal fibrosis: efficacy of octreotide and tamoxifen.

AbstractAIMS AND BACKGROUND:
Neuroendocrine tumors are uncommon clinical entities and only a few cases of the co-occurrence of neuroendocrine tumors and retroperitoneal fibrosis have been described in the literature.
METHODS AND STUDY DESIGN:
We report the promising results achieved in a case of neuroendocrine tumor complicated by retroperitoneal fibrosis causing right ureteral obstruction treated with long-acting release octreotide and tamoxifen.
RESULTS AND CONCLUSIONS:
The treatment resulted in a complete response without toxicity.
AuthorsElisa Biasco, Andrea Antonuzzo, Luca Galli, Giacomo Giulio Baldi, Lisa Derosa, Riccardo Marconcini, Azzurra Farnesi, Sergio Ricci, Alfredo Falcone
JournalTumori (Tumori) Vol. 101 Issue 1 Pg. e24-8 (Mar 20 2015) ISSN: 2038-2529 [Electronic] United States
PMID25702678 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antineoplastic Agents, Hormonal
  • Tamoxifen
  • Octreotide
Topics
  • Abdominal Pain (etiology)
  • Antineoplastic Agents, Hormonal (therapeutic use)
  • Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
  • Humans
  • Intestinal Neoplasms (pathology)
  • Intestine, Small
  • Male
  • Middle Aged
  • Neuroendocrine Tumors (complications, diagnosis, drug therapy, pathology)
  • Octreotide (administration & dosage)
  • Retroperitoneal Fibrosis (complications, diagnosis, drug therapy, etiology)
  • Tamoxifen (administration & dosage)
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Ureteral Obstruction (etiology)

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