HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

NIPT-based screening for Down syndrome and beyond: what do pregnant women think?

AbstractOBJECTIVE:
The aim of the study is to study pregnant women's views on noninvasive prenatal testing (NIPT) for Down syndrome and the potential to test for a broader range of conditions.
METHODS:
An online questionnaire available on the Dutch pregnancy fair website was completed by 381 pregnant women.
RESULTS:
Of the women, 51% expressed interest in having NIPT, including 33% of women who had declined first-trimester screening. The majority (73%) thought that the uptake of screening would increase with NIPT. Most women agreed that testing for life-threatening (89%), severe physical (79%), or severe mental (76%) disorders should be offered. A minority (29%) felt that prenatal screening should also be offered for late-onset disorders. Most (41%) preferred to have a free choice from a list of disorders, 31% preferred a 'closed offer', and 26% preferred choosing between packages of disorders. Although most women (76%) thought that screening for a broad range of conditions would avoid much suffering, 39% feared that it would confront couples with choices, the implications of which would be difficult to grasp.
CONCLUSION:
The results suggest that the uptake of screening will increase with NIPT. If NIPT will be offered for a broad range of conditions, it is crucial to find a way that facilitates rather than undermines well-informed decision-making.
AuthorsRachèl V van Schendel, Wybo J Dondorp, Danielle R M Timmermans, Eline J H van Hugte, Anne de Boer, Eva Pajkrt, Augusta M A Lachmeijer, Lidewij Henneman
JournalPrenatal diagnosis (Prenat Diagn) Vol. 35 Issue 6 Pg. 598-604 (Jun 2015) ISSN: 1097-0223 [Electronic] England
PMID25693726 (Publication Type: Journal Article)
Copyright© 2015 John Wiley & Sons, Ltd.
Chemical References
  • DNA
Topics
  • Adult
  • Attitude to Health
  • DNA (blood)
  • Down Syndrome (diagnosis)
  • Female
  • Humans
  • Netherlands
  • Pregnancy
  • Pregnant Women (psychology)
  • Prenatal Diagnosis (psychology)
  • Surveys and Questionnaires
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: