Abstract | OBJECTIVE: To study the outcome of pars plana vitrectomy performed on patients with stage 4b and stage 5 retinopathy of prematurity and to examine differences in clinical presentation from developed countries. DESIGN: Observational prospective case series. PARTICIPANTS: METHODS: The study was undertaken at a tertiary care ophthalmology centre in a developing country. Demographic variables, postnatal risk factors, and anatomic and visual status were noted preoperatively. Patients with stage 4b ROP underwent a 3-port lens-sparing vitrectomy. Those with stage 5 ROP additionally underwent lensectomy and retrolental membrane dissection. Patients were assessed on their last follow-up for anatomic, visual, and functional results. Statistical evaluation was performed using the nonparametric Wilcoxon rank sum test. RESULTS: The results were evaluated by number of eyes treated, except for functional score. In 21 patients, 31 eyes underwent operation, of which 20 were stage 4b and 11 were stage 5. Anatomic success was achieved in 18 eyes (90%) with stage 4b. Mean vision in this anatomically successful group was 3.765, and the functional score was 5.36. In stage 5 eyes, anatomic success was achieved in 5 eyes (45.45%). Mean vision in this anatomically successful group was 1.833, and the functional score was 3. The visual results of stage 4b cases, compared with stage 5, were significantly better (p=0.0387). CONCLUSIONS: Larger, older babies and previously unablated eyes presented with retinopathy of prematurity for surgery compared with developed countries. Anatomic, visual, and (notably) functional recovery was found in a good percentage of eyes.
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Authors | Salil Gadkari, Rushita Kamdar, Sucheta Kulkarni, Nilesh Kakade, Sudhir Taras, Madan Deshpande |
Journal | Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
(Can J Ophthalmol)
Vol. 50
Issue 1
Pg. 54-60
(Feb 2015)
ISSN: 1715-3360 [Electronic] England |
PMID | 25677284
(Publication Type: Journal Article, Observational Study, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2015 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved. |
Topics |
- Birth Weight
- Developing Countries
- Gestational Age
- Humans
- India
- Infant, Newborn
- Infant, Very Low Birth Weight
- Prospective Studies
- Retinal Detachment
(surgery)
- Retinopathy of Prematurity
(classification, diagnosis, surgery)
- Tomography, Optical Coherence
- Treatment Outcome
- Visual Acuity
(physiology)
- Vitrectomy
- Vitreoretinal Surgery
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