Renal oligo- and anhydramnios: cause, course and outcome--a single-center study.

Abstract

PURPOSE:

To evaluate the outcome of patients with renal oligohydramnios and explore the impact of patient variables on outcome and prognosis.

METHODS:

A retrospective single-center study was conducted analyzing 104 pregnancies complicated by oligohydramnios of renal origin from 2001 to 2011. Statistical analysis was performed to assess the influence of pre- and postnatal data on pregnancy outcome, morbidity and mortality.

RESULTS:

Prenatal renal diagnoses were as follows: hydronephrosis/megaureter: n = 21 (20.2 %), aberrance in renal form or location: n = 7 (6.7 %), cystic renal disease: n = 28 (26.9 %), renal dysplasia: n = 24 (23.1 %), renal agenesis: n = 42 (30.4 %), posterior urethral valves: n = 11 (10.6 %). Hydronephrosis/megaureter and late onset of oligohydramnios were prognostic factors for fetal survival, whereas renal agenesis and associated anomalies had a negative impact on pregnancy outcome. Prenatal interventions did not improve prognosis.

CONCLUSIONS:

Pregnancies complicated by renal oligohydramnios still have a poor outcome. Careful weighing of prognostic factors is necessary to decide about further therapeutic measures.

• Authors: Judith Eva Spiro, Martin Konrad, Esther Rieger-Fackeldey, Katja Masjosthusmann, Susanne Amler, Walter Klockenbusch, Ralf Schmitz
• Journal: Archives of gynecology and obstetrics (Arch Gynecol Obstet) Vol. 292 Issue 2 Pg. 327-36 (Aug 2015) ISSN: 1432-0711 [Electronic] Germany
• PMID: 25676656 (Publication Type: Journal Article)

Topics

• Abnormalities, Multiple (diagnostic imaging)
• Adult
• Congenital Abnormalities
• Female
• Humans
• Hydronephrosis (etiology)
• Kidney (abnormalities)
• Kidney Diseases (congenital)
• Kidney Tubules, Proximal (abnormalities)
• Male
• Oligohydramnios (etiology)
• Pregnancy
• Pregnancy Complications
• Pregnancy Outcome
• Prenatal Diagnosis (adverse effects, methods)
• Prognosis
• Retrospective Studies
• Ultrasonography, Prenatal (methods)
• Urogenital Abnormalities