Klebsiella species are a common cause of community- and nosocomial-acquired
pneumonia. Antibiotic resistance to the class of
carbapenem in patients with
pneumonia caused by Klebsiella species is unusual. New studies report
carbapenem resistance in patients with
pneumonia caused by Klebsiella species.This article examines, retrospectively, antibiotic resistance in patients with community- and nosocomial-acquired
pneumonia caused by Klebsiella species.The data of all patients with community- and nosocomial-acquired
pneumonia caused by Klebsiella species were collected from the hospital charts at the HELIOS Clinic, Witten/Herdecke University, Wuppertal, Germany, within the study period 2004 to 2014. An antibiogram was created from all of the study patients with
pneumonia caused by Klebsiella species. Sensitivity and resistance profiles were performed for the different
antibiotics that have been consistently used in the treatment of patients with
pneumonia caused by Klebsiella species. All demographic, clinical, and laboratory data of all of the patients with
pneumonia caused by Klebsiella species were collected from the patients' records.During the study period of January 1, 2004, to August 12, 2014, 149 patients were identified with community- and nosocomial-acquired
pneumonia affected by Klebsiella species. These patients had a mean age of 70.6 ± 13 (107 [71.8%, 95% CI 64.6%-79%] men and 42 [28.2%, 95% CI 21%-35.4%] women). In all of the patients with
pneumonia caused by Klebsiella species, there was resistance to
ampicillin (P < 0.0001). Many patients with
pneumonia caused by Klebsiella species (75.3%) also showed resistance to
piperacillin (P < 0.0001). However, no patients with
pneumonia caused by Klebsiella species showed resistance to
imipenem or
meropenem (P < 0.0001).Antibiotic resistance to the
antibiotic class of
carbapenem was not detected in patients with
pneumonia caused by Klebsiella species.