Negative pressure wound therapy applied before and after split-thickness skin graft helps healing of Fournier gangrene: a case report (CARE-Compliant).

Abstract

Fournier gangrene is a rare but highly infectious disease characterized by fulminant necrotizing fasciitis involving the genital and perineal regions. Negative pressure wound therapy (NPWT; KCI USA Inc, San Antonio, TX) is a widely adopted technique in many clinical settings. Nevertheless, its application and effect in the treatment of Fournier gangrene are unclear. A 47-year-old male patient was admitted with an anal abscess followed by a spread of the infection to the scrotum, which was caused by Pseudomonas aeruginosa. NPWT was applied on the surface of the scrotal area and continued for 10 days. A split-thickness skin graft from the scalp was then grafted to the wound, after which, NPWT utilizing gauze sealed with an occlusive dressing and connected to a wall suction was employed for 7 days to secure the skin graft. At discharge, the percentage of the grafted skin alive on the scrotum was 98%. The wound beside the anus had decreased to 4 × 0.5 cm with a depth of 1 cm. Follow-up at the clinic 1 month later showed that both wounds had healed. The patient did not complain of any pain or bleeding, and was satisfied with the outcome. NPWT before and after split-thickness skin grafts is safe, well tolerated, and efficacious in the treatment of Fournier gangrene.

• Authors: Junna Ye, Ting Xie, Minjie Wu, Pengwen Ni, Shuliang Lu
• Journal: Medicine (Medicine (Baltimore)) Vol. 94 Issue 5 Pg. e426 (Feb 2015) ISSN: 1536-5964 [Electronic] United States
• PMID: 25654376 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Fournier Gangrene (etiology, therapy)
• Humans
• Male
• Middle Aged
• Negative-Pressure Wound Therapy (methods)
• Pseudomonas Infections (complications)
• Skin Transplantation (methods)