Abstract | AIM: There is evidence that patients with the metabolic syndrome have altered platelet indices including higher mean platelet volume. According to the 2009 International Diabetes Federation criteria of metabolic syndrome diagnosis, elevated waist circumference (≥94 cm in M, ≥80 cm in F), as a determinant of abdominal obesity, is not an obligatory component. The aim of this study was to evaluate the relationship between platelet indices, including mean platelet volume, and abdominal obesity in patients with metabolic syndrome. METHODS: RESULTS: In group A, mean platelet volume was significantly higher than in group C (10.70 ± 1.01 vs. 10.35 ± 0.94 fL, p = 0.007). However, there was no difference in mean platelet volume between group A and B (10.70 ± 1,01vs. 10.63 ± 1.03 fL, p >0.05). Furthermore, in group A, mean platelet volume was correlated with waist circumference (r = 0.14, p = 0.041) and body mass index (r = 0.14, p = 0.045). In all study groups, a significant association between mean platelet volume and platelet count (r = -0.33, p <0.001) was found. CONCLUSION: In individuals with metabolic syndrome and abdominal obesity mean platelet volume is positively correlated with waist circumference and significantly higher than in patients without these abnormalities.
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Authors | Anna Furman-Niedziejko, Pawel Rostoff, Radoslaw Rychlak, Karolina Golinska-Grzybala, Magdalena Wilczynska-Golonka, Mateusz Golonka, Jadwiga Nessler |
Journal | Folia medica Cracoviensia
(Folia Med Cracov)
Vol. 54
Issue 2
Pg. 55-64
( 2014)
ISSN: 0015-5616 [Print] Poland |
PMID | 25648310
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Aged
- Blood Platelets
(metabolism)
- Body Mass Index
- Female
- Humans
- Male
- Metabolic Syndrome
(blood)
- Middle Aged
- Obesity, Abdominal
(blood)
- Platelet Count
- Risk Factors
- Waist Circumference
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