HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

A sorghum MYB transcription factor induces 3-deoxyanthocyanidins and enhances resistance against leaf blights in maize.

Abstract
Sorghum responds to the ingress of the fungal pathogen Colletotrichum sublineolum through the biosynthesis of 3-deoxyanthocyanidin phytoalexins at the site of primary infection. Biosynthesis of 3-deoxyanthocyanidins in sorghum requires a MYB transcription factor encoded by yellow seed1 (y1), an orthologue of the maize gene pericarp color1 (p1). Maize lines with a functional p1 and flavonoid structural genes do not produce foliar 3-deoxyanthocyanidins in response to fungal ingress. To perform a comparative metabolic analysis of sorghum and maize 3-deoxyanthocyanidin biosynthetic pathways, we developed transgenic maize lines expressing the sorghum y1 gene. In maize, the y1 transgene phenocopied p1-regulated pigment accumulation in the pericarp and cob glumes. LC-MS profiling of fungus-challenged Y1-maize leaves showed induction of 3-deoxyanthocyanidins, specifically luteolinidin. Y1-maize plants also induced constitutive and higher levels of flavonoids in leaves. In response to Colletotrichum graminicola, Y1-maize showed a resistance response.
AuthorsFarag Ibraheem, Iffa Gaffoor, Qixian Tan, Chi-Ren Shyu, Surinder Chopra
JournalMolecules (Basel, Switzerland) (Molecules) Vol. 20 Issue 2 Pg. 2388-404 (Jan 30 2015) ISSN: 1420-3049 [Electronic] Switzerland
PMID25647576 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S.)
Chemical References
  • Anthocyanins
  • Flavonoids
  • Plant Proteins
  • Transcription Factors
Topics
  • Anthocyanins (metabolism)
  • Colletotrichum (physiology)
  • Disease Resistance
  • Flavonoids (metabolism)
  • Host-Pathogen Interactions
  • Pigmentation
  • Plant Diseases (microbiology)
  • Plant Leaves (genetics, metabolism, microbiology)
  • Plant Proteins (biosynthesis, genetics)
  • Plants, Genetically Modified
  • Sorghum (genetics)
  • Transcription Factors (biosynthesis, genetics)
  • Zea mays (genetics, metabolism, microbiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: