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Botanicals: an alternative remedy to radiotherapy-induced dysuria.

Abstract
Everyday, many patients get radiotherapy for prostatic, rectal, uterine cervix and other pelvic organs cancer. Dysuria is common in pelvic, especially prostate radiotherapy, but there is not any established and confirmed treatment for this therapeutic side effect. Therefore, an alternative therapeutic method, using herbal preparation, may be an effective solution. This study seeks a defensible suggestion in Iranian Traditional Medicine (ITM). In ITM, a few medicinal herbs such as Plantago psyllium, Cydonia oblonga, Portulaca oleracea and some species of Malvaceae and Cucurbitaceae family are indicated in treating dysuria secondary to urethral moisturizing layer defect and inflammatory disorders. Most of these herbs have mucilaginous characteristics and tissue regeneration ability. This choice can be an appropriate one for radiotherapy-induced dysuria as it is produced by a similar pathophysiology with bladder cell layer injury and urethritis. Pharmacological properties such as anti-oxidant, anti-inflammatory, and anti-ulcerogenic activity of the offered herbs make its use justifiable. In lack of sufficient clinical trials to clarify the clinical outcome, further clinical investigation seems to be necessary.
AuthorsAmir Mohammad Jaladat, Fatemeh Atarzadeh, Hossein Rezaeizadeh, Bahram Mofid, Ahmad Mosalaie, Farshid Farhan, Gholamreza Amin
JournalComplementary therapies in medicine (Complement Ther Med) Vol. 23 Issue 1 Pg. 90-9 (Feb 2015) ISSN: 1873-6963 [Electronic] Scotland
PMID25637157 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
CopyrightCopyright © 2014 Elsevier Ltd. All rights reserved.
Chemical References
  • Drugs, Chinese Herbal
Topics
  • Drugs, Chinese Herbal (therapeutic use)
  • Dysuria (drug therapy)
  • Humans
  • Medicine, Traditional (methods)
  • Phytotherapy (methods)
  • Plants, Medicinal
  • Radiotherapy (adverse effects)

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