Abstract | BACKGROUND: METHODS: A retrospective analysis of all patients who underwent reconstruction for inflammatory breast cancer from January of 2000 to December of 2012 was conducted. RESULTS: Of 830 inflammatory breast cancer patients, 59 (7.1 percent; median age, 48 years; range, 27 to 65 years) underwent free flap reconstruction. All patients received chemotherapy and radiation therapy. Most patients (n = 52) underwent delayed reconstruction. Five patients with a history of prior partial mastectomy and irradiation developed inflammatory breast cancer and underwent immediate reconstruction following completion mastectomy. Two others underwent immediate chest wall and breast reconstruction following resection. Thirteen patients underwent bilateral reconstruction, and seven required a bipedicled abdominal flap for the unilateral mastectomy defect. Thirty-seven patients (62.7 percent) required revision of the reconstructed breast, and 29 (49.2 percent) had a contralateral balancing procedure to optimize symmetry. Complications occurred in 21 patients (35.6 percent), with one total flap loss (1.7 percent). The median length of follow-up was 43.9 months; 49 patients (83.1 percent) were alive without evidence of recurrent disease. CONCLUSIONS: CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.
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Authors | Edward I Chang, Eric I Chang, Ran Ito, Hong Zhang, Alexander T Nguyen, Roman J Skoracki, Matthew M Hanasono, Melissa A Crosby, Naoto T Ueno, Kelly K Hunt |
Journal | Plastic and reconstructive surgery
(Plast Reconstr Surg)
Vol. 135
Issue 2
Pg. 262e-269e
(Feb 2015)
ISSN: 1529-4242 [Electronic] United States |
PMID | 25626809
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Adult
- Aged
- Carcinoma
(drug therapy, radiotherapy, surgery)
- Chemotherapy, Adjuvant
- Combined Modality Therapy
- Disease-Free Survival
- Female
- Follow-Up Studies
- Free Tissue Flaps
(statistics & numerical data)
- Humans
- Inflammatory Breast Neoplasms
(drug therapy, radiotherapy, surgery)
- Kaplan-Meier Estimate
- Mammaplasty
(methods, statistics & numerical data)
- Mastectomy
(methods)
- Middle Aged
- Neoplasms, Multiple Primary
(drug therapy, radiotherapy, surgery)
- Postoperative Complications
(epidemiology)
- Prognosis
- Radiotherapy, Adjuvant
- Retrospective Studies
- Thoracic Wall
(surgery)
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