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Combined inhalation and oral supplementation of Vitamin A and Vitamin D: a possible prevention and therapy for tuberculosis.

Abstract
Tuberculosis is continuing as a problem of mankind. With evolution, MDR and XDR forms of tuberculosis have emerged from drug sensitive strain. MDR and XDR strains are resistant to most of the antibiotics, making the management more difficult. BCG vaccine is not providing complete protection against tuberculosis. Therefore new infections are spreading at a tremendous rate. At the present moment there is experimental evidence to believe that Vitamin A and Vitamin D has anti-mycobacterial property. It is in this context, we have hypothesized a host based approach using the above vitamins that can cause possible prevention and cure of tuberculosis with minimal chance of resistance or toxicity.
AuthorsKirtimaan Syal, Surajit Chakraborty, Rajasri Bhattacharyya, Dibyajyoti Banerjee
JournalMedical hypotheses (Med Hypotheses) Vol. 84 Issue 3 Pg. 199-203 (Mar 2015) ISSN: 1532-2777 [Electronic] United States
PMID25617043 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
CopyrightCopyright © 2015 Elsevier Ltd. All rights reserved.
Chemical References
  • Antibiotics, Antitubercular
  • Drug Combinations
  • Vitamin A
  • Vitamin D
Topics
  • Administration, Inhalation
  • Administration, Oral
  • Antibiotics, Antitubercular (therapeutic use)
  • Drug Combinations
  • Humans
  • Models, Biological
  • Tuberculosis (prevention & control)
  • Vitamin A (administration & dosage, therapeutic use)
  • Vitamin D (administration & dosage, therapeutic use)

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