Coronary artery bypass grafting in 2 thrombophilic patients with protein s deficiency.

In this report, we review 2 cases of coronary revascularization in patients with a diagnosis of coronary artery disease and preoperative protein S deficiency, an established hypercoagulable condition. In an attempt to normalize protein S levels, fresh frozen plasma was used as the priming fluid for the cardiopulmonary bypass circuit before the initiation of extracorporeal circulation. On the basis of a low risk of bleeding and the theoretical risk of thrombosis, neither patient received intraoperative antifibrinolytic treatment nor did they develop perioperative thrombotic complications.
AuthorsYen-Michael S Hsu, George J Despotis
JournalA & A case reports (A A Case Rep) Vol. 2 Issue 8 Pg. 92-4 (Apr 15 2014) ISSN: 2325-7237 [Electronic] United States
PMID25611767 (Publication Type: Journal Article)

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