Abstract | BACKGROUND: METHODS: RESULTS: The prevalence of dyslipidemia was comparable among Group IGM+SH+, Group IGM+SH- and IGM+ controls (57.9, 58.4, 56%, P = NS). No difference in dyslipidemia prevalence among IGM- patients and IGM- controls was observed. The IGM+SH+ patients had a higher prevalence of dyslipidemia (57.9%) than IGM-SH+ ones (29.1%, P < 0.01). The IGM+SH- patients showed an increased prevalence of hypertension (76.6 vs 54.8%, P < 0.01) and dyslipidemia (58.4 vs 23.8%, P < 0.0001) as compared with IGM-SH- patients. Logistic regression analysis showed that only IGM was associated to dyslipidemia (OR 4.31, 95% CI 2.61-7.12, P = 0.0001) regardless of age, SH and gender. CONCLUSIONS: In the absence of alterations of glucose metabolism the presence of a subtle cortisol excess has no effect on lipid pattern. IGM seems to influence the lipid metabolism regardless of the presence of SH.
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Authors | B Masserini, V Morelli, S Palmieri, C Eller-Vainicher, V Zhukouskaya, E Cairoli, E Orsi, P Beck-Peccoz, A Spada, I Chiodini |
Journal | Journal of endocrinological investigation
(J Endocrinol Invest)
Vol. 38
Issue 6
Pg. 623-8
(Jun 2015)
ISSN: 1720-8386 [Electronic] Italy |
PMID | 25608646
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adrenal Gland Neoplasms
(blood, epidemiology, pathology)
- Aged
- Comorbidity
- Cushing Syndrome
(blood, epidemiology, pathology)
- Dyslipidemias
(blood, epidemiology, pathology)
- Female
- Glucose Intolerance
(blood, epidemiology, pathology)
- Humans
- Lipids
(blood)
- Male
- Middle Aged
- Prevalence
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