[The importance of food and drug plant factors in the combined treatment of patients with type-II diabetes mellitus].

Abstract

A study was made of the effect of natural (vegetable dish) and refined (food methylcellulose--MC-100 and citrus pectin) vegetable fibers and Arfazetin (antidiabetic species, USSR) on the level of glucose, immunoreactive insulin (IRI), C-peptide, glucagon and gastrin in the blood of 41 patients with type II diabetes mellitus. These parameters were investigated on an empty stomach, 1, 2 and 4 h after breakfast I with a standard set of foodstuffs and minimum content of nutritive fibers. Similar investigations were conducted after intake of the same breakfast I in combination with various vegetable components. All the vegetable factors under study were shown to contribute to a decrease in a value of a glycemic rise noted after food intake. A vegetable dish and Arfazetin equally caused a significant rise of IRI secretion and C-peptide 60-90 min. after breakfast. MC-100 and particularly pectin decreased IRI and C-peptide secretion. There was a significant rise of gastrin secretion 1, 2 and 4 h when pectin was added to breakfast. When Arfazetin, a vegetable dish and MC-100 were added to breakfast I, a tendency to a rise of serum gastrin was observed 1 h after breakfast. The level of IRG during investigations with vegetable components did not differ from the results of investigations without these components.

• Authors: V D Korotkova, A A Perelygina, M B Antsiferov, A M Lobanova, T E Trumpe
• Journal: Problemy endokrinologii (Probl Endokrinol (Mosk)) 1989 Nov-Dec Vol. 35 Issue 6 Pg. 24-9 ISSN: 0375-9660 [Print] Russia (Federation)
• Vernacular Title: Znachenie pishchevykh i lekarstvennykh rastitel'nykh faktorov v kompleksnom lechenii bol'nykh sakharnym diabetom II tipa.
• PMID: 2560185 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Blood Glucose
• C-Peptide
• Dietary Fiber
• Gastrins
• Hypoglycemic Agents
• Insulin Antibodies
• Plant Extracts
• arfazetin
• Glucagon

Topics

• Adult
• Blood Glucose (analysis)
• C-Peptide (blood)
• Combined Modality Therapy
• Diabetes Mellitus, Type 2 (blood, therapy)
• Diet, Diabetic
• Dietary Fiber (therapeutic use)
• Gastrins (blood)
• Glucagon (blood)
• Humans
• Hypoglycemic Agents (therapeutic use)
• Insulin Antibodies (analysis)
• Middle Aged
• Plant Extracts (therapeutic use)