Abstract | BACKGROUND: Sedation is a condition of reduced level of consciousness (LOC) for a patient that is created to decrease irritability, anxiety, and restlessness. OBJECTIVES: PATIENTS AND METHODS: Based on the double-blind randomized clinical trial in this investigation, 80 children, who needed to repair their wounds with suture were randomly divided into two groups: group 1 and group 2, who have received oral diphenhydramine and oral ketamine, midazolam, and atropine cocktail, respectively. Behavioral changes were collected and recorded before, during intervention and two weeks after intervention. Statistical data were analyzed by SPSS-16 software and chi-square and Mann-Whitney U tests were employed to study the relations among variables. P < 0.05 was considered statistically significant. RESULTS: There was no significant difference between two groups in terms of drug acceptance and anxiety degree in children before intervention. Group 2 had achieved better and deeper sedation than group 1 during 45-minute post-medication (P < 0.05, P = 0.01). Regarding pediatric general behavior such as crying or interruptive moves, there was also a significant statistical difference between group 2 and group 1 (P = 0.009) based on Houpt Classification. The mean recovery times in groups 1 and 2 were 34.37 ± 14.23 min and 27.25 ± 5.14 min, respectively (P = 0.003). In terms of behavioral changes, the rate of cumulative frequency was computed for behavioral changes two weeks after the discharge from emergency department in which there were less behavioral changes in group 2 than in group 1 (P = 0.04). CONCLUSIONS:
|
Authors | Hassan Soleimanpour, Ata Mahmoodpoor, Farid Eftekhari Milani, Kavous Shahsavari Nia, Robab Mehdizadeh Esfanjani, Saeid Safari |
Journal | Iranian Red Crescent medical journal
(Iran Red Crescent Med J)
Vol. 16
Issue 9
Pg. e21366
(Sep 2014)
ISSN: 2074-1804 [Print] Estonia |
PMID | 25593736
(Publication Type: Journal Article)
|