Clinical evaluation of Moro (Citrus sinensis (L.) Osbeck) orange juice supplementation for the weight management.

Abstract

In the last years, several studies have recently evaluated the beneficial effects of red orange juice (Citrus sinensis (L.) Osbeck) and its active components in weight management and obesity. Moro orange is a cultivar of red orange, particularly rich in active compounds such as anthocyanins, hydroxycinnamic acids, flavone glycosides and ascorbic acid, which displays anti-obesity effects in in vitro and in vivo studies. In this clinical study, the effect of a Moro juice extract (Morosil(®), 400 mg/die) supplementation was evaluated in overweight healthy human volunteers for 12 weeks. Results showed that Moro juice extract intake was able to induce a significant reduction in body mass index (BMI) after 4 weeks of treatment (p < 0.05). Moreover, in subjects treated with Moro extract, body weight, BMI, waist and hip circumference were significantly different from the placebo group (p < 0.05). In conclusion, it could be suggested that the active compounds contained in Moro juice have a synergistic effect on fat accumulation in humans and Moro juice extract can be used in weight management and in the prevention of human obesity.

• Authors: Venera Cardile, Adriana Carol Eleonora Graziano, Alessandro Venditti
• Journal: Natural product research (Nat Prod Res) Vol. 29 Issue 23 Pg. 2256-60 ( 2015) ISSN: 1478-6427 [Electronic] England
• PMID: 25588369 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Plant Extracts

Topics

• Adult
• Body Mass Index
• Citrus sinensis
• Dietary Supplements
• Double-Blind Method
• Fruit and Vegetable Juices
• Humans
• Middle Aged
• Overweight (drug therapy)
• Plant Extracts (pharmacology)
• Waist Circumference
• Weight Loss
• Young Adult