Abstract | AIM: PATIENTS AND METHODS: Forty-nine stage III b or stage IV inoperable NSCLC patients were divided into two groups, depending on whether albumin administration was given before chemotherapy. The Karnofsky performance score (KPS), nutritional status including body mass index (BMI), and serum albumin level were evaluated. SIR was evaluated by investigating the changes of the C-reactive protein (CRP), calculating the neutrophil lymphocyte ratio (NLR), and the platelet lymphocyte ratio (PLR), before and after chemotherapy. The chemotherapy-induced toxicity was also evaluated. RESULTS: CONCLUSION: Early assessment of the serum albumin level in patients with inoperable NSCLC and their improvement in the serum albumin level may suggest that there are beneficial effects after chemotherapy.
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Authors | Xingsheng Wang, Hongli Han, Qi Duan, Uzair Khan, Yonghao Hu, Xiaomei Yao |
Journal | Journal of cancer research and therapeutics
(J Cancer Res Ther)
2014 Oct-Dec
Vol. 10
Issue 4
Pg. 1019-23
ISSN: 1998-4138 [Electronic] India |
PMID | 25579547
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antineoplastic Agents
- Serum Albumin
- C-Reactive Protein
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Topics |
- Aged
- Aged, 80 and over
- Antineoplastic Agents
(therapeutic use)
- Body Mass Index
- C-Reactive Protein
(metabolism)
- Carcinoma, Non-Small-Cell Lung
(blood, drug therapy, metabolism)
- Female
- Humans
- Inflammation
(drug therapy)
- Karnofsky Performance Status
- Lung Neoplasms
(blood, drug therapy, metabolism)
- Lymphocytes
(cytology)
- Male
- Middle Aged
- Neutrophils
(metabolism)
- Prognosis
- Serum Albumin
(metabolism)
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