Disseminated adenovirus disease in heart transplant recipient presenting with conjunctivitis.

Abstract

We report a 65-year-old heart transplant recipient who presented with conjunctivitis, likely acquired from a family member who worked at a daycare center during an outbreak of conjunctivitis. He developed a severe adenoviral pneumonitis, which was successfully treated with intravenous cidofovir combined with a reduction of immunosuppression.

• Authors: J Bruminhent, D M Athas, B D Hess, P Flomenberg
• Journal: Transplant infectious disease : an official journal of the Transplantation Society (Transpl Infect Dis) Vol. 17 Issue 1 Pg. 125-8 (Feb 2015) ISSN: 1399-3062 [Electronic] Denmark
• PMID: 25571908 (Publication Type: Case Reports, Journal Article)
• Copyright: © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Chemical References

• Antiviral Agents
• Organophosphonates
• Cytosine
• Cidofovir

Topics

• Adenovirus Infections, Human (drug therapy)
• Adenoviruses, Human (drug effects)
• Aged
• Antiviral Agents (therapeutic use)
• Cidofovir
• Conjunctivitis (drug therapy)
• Cytosine (analogs & derivatives, therapeutic use)
• Heart Transplantation (adverse effects)
• Humans
• Immunocompromised Host
• Immunosuppression Therapy (adverse effects)
• Male
• Organophosphonates (therapeutic use)
• Pneumonia, Viral (drug therapy)
• Postoperative Complications (drug therapy)
• Transplant Recipients