HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Time varying effective connectivity for describing brain network changes induced by a memory rehabilitation treatment.

Abstract
In clinical practice, cognitive impairment is often observed after stroke. The efficacy of rehabilitative interventions is routinely assessed by means of a neuropsychological test battery. Nowadays, more evidences indicate that the neuroplasticity which occurs after stroke can be better understood by investigating changes in brain networks. In this study we applied advanced methodologies for effective connectivity estimation in combination with graph theory approach, to define EEG derived descriptors of brain networks underlying memory tasks. In particular, we proposed such descriptors to identify substrates of efficacy of a Brain-Computer Interface (BCI) controlled neurofeedback intervention to improve cognitive function after stroke. Electroencephalographic (EEG) data were collected from two stroke patients before and after a neurofeedback-based training for memory deficits. We show that the estimated brain connectivity indices were sensitive to different training intervention outcomes, thus suggesting an effective support to the neuropsychological assessment in the evaluation of the changes induced by the BCI-based cognitive rehabilitative intervention.
AuthorsJ Toppi, D Mattia, A Anzolin, M Risetti, M Petti, F Cincotti, F Babiloni, L Astolfi
JournalConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference (Conf Proc IEEE Eng Med Biol Soc) Vol. 2014 Pg. 6786-9 ( 2014) ISSN: 1557-170X [Print] United States
PMID25571554 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Aged
  • Brain (physiopathology)
  • Brain Waves
  • Cognition
  • Cognition Disorders (physiopathology, psychology, rehabilitation)
  • Electroencephalography
  • Female
  • Humans
  • Male
  • Memory
  • Memory Disorders (physiopathology, psychology, rehabilitation)
  • Nerve Net (physiopathology)
  • Neurofeedback
  • Neuropsychological Tests
  • Stroke (physiopathology, psychology, rehabilitation)
  • Treatment Outcome
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: