Occupational inhalation of aniline fumes induced methemoglobinemea and hemolytic anemia precipitated days later.

Abstract

Methylene blue is utilized as the main treatment of methemoglobinemia. Here we report two cases, in which patient suffered from aniline-induced methemoglobinemia with initial good response but later developed haemolytic anemia due to methylene blue therapy. He was treated with hydration, high flow oxygen and steroid therapy. Caution should be exercised while using methylene blue as antidote of acute methemoglobinemia as both methemoglobinemia and its antidote methylene blue can itself precipitate fatal haemolytic anemia.

• Authors: Ys Ravi Kumar, Manthappa, Prasanna Kumar, Mc Prasad, Ar Radhika, Amarendra Chowdary Edara
• Journal: Indian journal of occupational and environmental medicine (Indian J Occup Environ Med) Vol. 18 Issue 2 Pg. 95-6 (May 2014) ISSN: 0973-2284 [Print] India
• PMID: 25568605 (Publication Type: Case Reports)