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A magnetic polyaniline nanohybrid for MR imaging and redox sensing of cancer cells.

Abstract
A synthetic process for constructing an organo-metal nanohybrid is described. This process uses polyaniline as a ligand in order to fabricate magnetic nanoparticles. This nanohybrid shows imaging potential uses as a magnetic resonance imaging contrast agent and a redox-sensing probe simultaneously both in vitro and in vivo.
AuthorsYoochan Hong, Seungyeon Hwang, Dan Heo, Bongjune Kim, Minhee Ku, Eugene Lee, Seungjoo Haam, Dae Sung Yoon, Jaemoon Yang, Jin-Suck Suh
JournalNanoscale (Nanoscale) Vol. 7 Issue 5 Pg. 1661-6 (Feb 07 2015) ISSN: 2040-3372 [Electronic] England
PMID25559644 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Aniline Compounds
  • Contrast Media
  • polyaniline
  • Matrix Metalloproteinase 1
Topics
  • Aniline Compounds (chemistry)
  • Animals
  • Cell Line, Tumor
  • Cell Survival (drug effects)
  • Contrast Media (chemistry, pharmacology, toxicity)
  • Humans
  • MCF-7 Cells
  • Magnetic Resonance Imaging
  • Magnetics
  • Matrix Metalloproteinase 1 (metabolism)
  • Mice
  • Nanoparticles (chemistry)
  • Neoplasms (diagnostic imaging, pathology)
  • Oxidation-Reduction
  • Radiography
  • Transplantation, Heterologous

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