Abstract |
115 women, distributed in 20 centres, were included in a randomized study designed to assess the efficacy of Polygynax in preventing vaginal infections in women at risk, at the start of pregnancy. Polygynax proved to be markedly effective since only 9.6% of the patients in the Polygynax group had a vaginal infection, in contrast to 42.6% of the patients in the control group. This result is highly significant (p less than 0.0001) and confirms the advantage attached to the use of Polygynax when a first line treatment involving the use of several drugs in combination is indicated.
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Authors | A J Audebert |
Journal | Revue francaise de gynecologie et d'obstetrique
(Rev Fr Gynecol Obstet)
Vol. 84
Issue 3 Pt 2
Pg. 287-90
(Mar 25 1989)
ISSN: 0035-290X [Print] France |
Vernacular Title | Utilisation de Polygynax chez la femme enceinte en prévention des infections cervico-vaginales. |
PMID | 2555894
(Publication Type: Clinical Trial, Journal Article, Multicenter Study, Randomized Controlled Trial)
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Chemical References |
- Arsenicals
- Drug Combinations
- Polymyxins
- Nystatin
- acetarsol, dimethicone, neomycin, nystatin, polymyxin drug combination
- Neomycin
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Topics |
- Adult
- Arsenicals
(therapeutic use)
- Bacterial Infections
(prevention & control)
- Clinical Trials as Topic
- Drug Combinations
(therapeutic use)
- Drug Evaluation
- Female
- Humans
- Multicenter Studies as Topic
- Neomycin
(therapeutic use)
- Nystatin
(therapeutic use)
- Polymyxins
(therapeutic use)
- Pregnancy
- Pregnancy Complications, Infectious
(prevention & control)
- Random Allocation
- Uterine Cervical Diseases
(prevention & control)
- Vaginal Diseases
(prevention & control)
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