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Disease caused by rotavirus infection.

Abstract
Although rotavirus vaccines are available, rotaviruses remain the major cause of childhood diarrheal disease worldwide. The Rotarix (GlaxoSmithKline Biologicals Rixensart, Belgium) and RotaTeq (Merck and Co., Inc. Whitehouse Station, New Jersey, USA) vaccines are effective for reducing the morbidity and mortality of rotavirus infection. This article aims to assess the epidemiology of rotaviral gastroenteritis and the efficacy and effectiveness of licensed rotavirus vaccines. This review concludes by presenting challenges in the field that require further exploration by and perspectives from basic and translational research in the future.
AuthorsChe-Liang Lin, Shou-Chien Chen, Shyun-Yeu Liu, Kow-Tong Chen
JournalThe open virology journal (Open Virol J) Vol. 8 Pg. 14-9 ( 2014) ISSN: 1874-3579 [Print] United Arab Emirates
PMID25553142 (Publication Type: Journal Article)

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