Ceftriaxone-induced acute encephalopathy in a peritoneal dialysis patient.

Abstract

Encephalopathy is a rare side effect of third and fourth generation cephalosporins. Renal failure and preexisting neurological disease are notable risk factors. Recognition is important as discontinuing the offending agent usually resolves symptoms. We present a case of acute encephalopathy in a patient with end stage renal disease (ESRD) treated with peritoneal dialysis (PD) who received intravenous ceftriaxone for peritonitis. This case illustrates the potential severe neurologic effects of cephalosporins, which are recommended by international guidelines as first-line antimicrobial therapy for spontaneous bacterial peritonitis.

• Authors: Sami Safadi, Michael Mao, John J Dillon
• Journal: Case reports in nephrology (Case Rep Nephrol) Vol. 2014 Pg. 108185 ( 2014) ISSN: 2090-6641 [Print] United States
• PMID: 25544915 (Publication Type: Journal Article)