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Efficacy of expressed breast milk in reducing pain during ROP screening--a randomized controlled trial.

AbstractOBJECTIVE:
To assess the effectiveness of expressed breast milk (EBM) on neonatal pain during screening for retinopathy of prematurity (ROP).
METHODS:
Neonates who were on oral feeds undergoing ROP screening were included. Babies were randomized into intervention group (EBM + Standard practice) and control group. The standard practice is proparacaine, nesting and swaddling. Pain was assessed by PIPP scale, during and at 1 and 5 min after the procedure by the principal investigator who was blinded.
RESULTS:
The groups were similar in baseline characteristics. The group receiving EBM had significantly lower PIPP scores during the procedure 12.7 ± 1.69 compared to the control group 15.5 ± 1.78 (p < 0.05). The beneficial effect persisted at 1 min and 5 min after the procedure 6.20 ± 1.9 vs. 12.4 ± 2.54 (p ≤ 0.05) at 1 min; 3.2 ± 1.5 and 6.85 ± 2.4 (p < 0.05) at 5 min.
CONCLUSION:
Oral EBM significantly reduces pain during and after ROP screening.
AuthorsLalitha Rosali, Saudamini Nesargi, Shiny Mathew, Usha Vasu, Suman P N Rao, Swarnarekha Bhat
JournalJournal of tropical pediatrics (J Trop Pediatr) Vol. 61 Issue 2 Pg. 135-8 (Apr 2015) ISSN: 1465-3664 [Electronic] England
PMID25541552 (Publication Type: Journal Article, Randomized Controlled Trial)
Copyright© The Author [2014]. Published by Oxford University Press. All rights reserved. For Permissions, please email: [email protected].
Chemical References
  • Anesthetics, Local
  • proxymetacaine
  • Propoxycaine
Topics
  • Anesthetics, Local (administration & dosage)
  • Breast Feeding
  • Double-Blind Method
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Mass Screening
  • Milk, Human
  • Outcome Assessment, Health Care
  • Pain (physiopathology, prevention & control)
  • Pain Measurement (methods)
  • Propoxycaine (administration & dosage)
  • Retinopathy of Prematurity (diagnosis)
  • Vision Screening (methods)

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