Abstract | BACKGROUND: Frictional dermal melanosis over bony prominences (Lifa disease) is a common pigmentary skin disorder in Iraqi patients. Q-switched lasers are the gold standard treatment of correcting pigmentation; among them are the 532-nm and 1,064-nm lasers. OBJECTIVE: PATIENTS AND METHODS: A prospective, comparative, controlled, split-lesion clinical trial study was designed. Nineteen female patients with clinical diagnosis of Lifa disease were enrolled. Each patient was treated for 3 sessions at 2-week intervals. A 532-nm Q-switched Nd:YAG laser was used on the left side and 1,064-nm on the right side of each lesion. Both objective and subjective parameters were assessed 1 and 3 months after the last treatment session. Darkness score, photographic assessment and patient satisfaction, and improvement of itch were recorded, respectively. RESULTS: Seventeen patients completed the study. The color score changes of both sides demonstrated that although both lasers were effective in reducing the pigmentation, the 1,064-nm wavelength had a more significant response. Similar results were obtained for the photographic evaluations and patient satisfaction scores. These changes were sustained throughout the 3 month follow-up. CONCLUSION: Both lasers were effective in the treatment of pigmentation abnormalities caused by Lifa disease. However, the efficacy was greater with the 1,064-nm wavelength.
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Authors | Muhsin A Al-Dhalimi, Azar H Maluki, Amir Tauma |
Journal | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
(Dermatol Surg)
Vol. 41
Issue 1
Pg. 136-41
(Jan 2015)
ISSN: 1524-4725 [Electronic] United States |
PMID | 25533157
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Adult
- Cosmetic Techniques
- Female
- Friction
- Humans
- Lasers, Solid-State
(adverse effects, therapeutic use)
- Melanosis
(etiology, surgery)
- Middle Aged
- Patient Satisfaction
- Pigmentation
- Prospective Studies
- Severity of Illness Index
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