WU polyomavirus in respiratory epithelial cells from lung transplant patient with Job syndrome.

Abstract

We detected WU polyomavirus (WUPyV) in a bronchoalveolar lavage sample from lungs transplanted into a recipient with Job syndrome by using immunoassays specific for the WUPyV viral protein 1. Co-staining for an epithelial cell marker identified most WUPyV viral protein 1-positive cells as respiratory epithelial cells.

• Authors: Erica A Siebrasse, Diana V Pastrana, Nang L Nguyen, Annie Wang, Mark J Roth, Steven M Holland, Alexandra F Freeman, John McDyer, Christopher B Buck, David Wang
• Journal: Emerging infectious diseases (Emerg Infect Dis) Vol. 21 Issue 1 Pg. 103-6 (Jan 2015) ISSN: 1080-6059 [Electronic] United States
• PMID: 25531075 (Publication Type: Case Reports, Journal Article, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, Non-P.H.S.)

Topics

• Adult
• Female
• HEK293 Cells
• Humans
• Job Syndrome (surgery, virology)
• Lung Transplantation
• Polyomavirus (genetics, isolation & purification)
• Polyomavirus Infections (diagnosis, virology)
• Respiratory Mucosa (virology)