[Anabolic effects of sodium selenite, vitamin E and retabolil in experimental hypotrophy induced by a pesticide].

Abstract

Forty Chinchilla rabbits of both sexes were examined for changes in some parameters of protein, lipid and trace elements metabolism (total protein, protein fractions, urea, residual nitrogen in blood serum, lipids, total cholesterol, free cholesterol, diglycerides, phospholipids, triglycerides, free fatty acids and the trace elements selenium, iron, zinc and so forth in the liver) during the animals' poisoning with the defoliant magnesium chlorate. A study was made of the effect on these changes of the administration for 3 weeks of sodium selenite (15 micrograms/kg), vitamin E (25 mg/kg) and retabolil (2 mg/kg once a week). It has been established that the combined administration of these agents removes and prevents the changes in protein, lipid and trace elements (hypoproteinemia, dysproteinemia and impairment of the nitrous balance) and lipid metabolism because of the animals' poisoning with magnesium chlorate.

• Authors: T M Makhmudov, M N Makhsumov, V Z Mazgutov
• Journal: Voprosy pitaniia (Vopr Pitan) 1989 May-Jun Issue 3 Pg. 61-4 ISSN: 0042-8833 [Print] Russia (Federation)
• Vernacular Title: Anabolicheskiĭ éffekt selenita natriia, vitamina E, retabolila na fone éksperimental'noĭ gipotrofii, vyzvannoĭ pestitsidom.
• PMID: 2552678 (Publication Type: Journal Article)

Chemical References

• Anabolic Agents
• Chlorates
• Herbicides
• Magnesium Compounds
• Vitamin E
• Nandrolone
• Nandrolone Decanoate
• Selenium
• Sodium Selenite
• Magnesium
• magnesium chlorate

Topics

• Anabolic Agents (pharmacology)
• Animals
• Chlorates (poisoning)
• Female
• Herbicides (poisoning)
• Magnesium (poisoning)
• Magnesium Compounds
• Male
• Nandrolone (analogs & derivatives, pharmacology)
• Nandrolone Decanoate
• Protein Deficiency (chemically induced, metabolism)
• Rabbits
• Selenium (pharmacology)
• Sodium Selenite
• Vitamin E (pharmacology)