Abstract | BACKGROUND: Struma testis is a rare entity, and there are only few reports on the malignant transformation of a testicular teratoma to papillary thyroid carcinoma in the literature. In this report, we describe the malignant transformation of struma testis with distant lung metastasis associated with trisomy 17 and a coexisting papillary microcarcinoma in the thyroid. CASE REPORT: CONCLUSION: To our knowledge, this is the first case of papillary thyroid cancer in struma testes metastatic to the lung. It highlights the difficulties in treating these patients. Surgery to remove cancer foci, followed by radioactive iodine ablation, resulted in an excellent response in our patient. Interestingly, trisomy 17, which has so far been observed only in noninvasive thyroid nodules, was associated with pulmonary metastasis in our patient.
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Authors | Shadi Barakat, Jamie Odem, Jacqueline R Batanian, Shahzad Raza, Uzma Z Khan |
Journal | Case reports in oncology
(Case Rep Oncol)
Vol. 7
Issue 3
Pg. 751-7
(Sep 2014)
ISSN: 1662-6575 [Print] Switzerland |
PMID | 25520651
(Publication Type: Case Reports)
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