Clinical safety of chemotherapy for elderly cancer patients complicated with hypertension.

Abstract

OBJECTIVE:

To access the safety of chemotherapy for elderly cancer patients complicated with hypertension.

METHODS:

Elderly cancer patients who were complicated with hypertension and treated by chemotherapy were recruited. All patients were treated by chemotherapy after an intervention on hypertension by psychotherapy, exercise guidance, salt regulation and nutrition support, therapy on hypertension, as well as prevention on hypertension associated complications.

RESULTS:

In 68 eligible patients, two suspended chemotherapy because of adverse reactions and 4 because of disease progression. The remaining 62 patients completed chemotherapy smoothly based on good hypertension control.

CONCLUSION:

With effective control of blood pressure, chemotherapy for elderly cancer patients complicated with hypertension is generally safe.

• Authors: Ya-Dong Qian, Xu Xu, Lin Wang, Xin-En Huang
• Journal: Asian Pacific journal of cancer prevention : APJCP (Asian Pac J Cancer Prev) Vol. 15 Issue 22 Pg. 9875-7 ( 2014) ISSN: 2476-762X [Electronic] Thailand
• PMID: 25520121 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Aged
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Blood Pressure Determination
• Female
• Follow-Up Studies
• Humans
• Hypertension (complications, physiopathology)
• Male
• Neoplasm Staging
• Neoplasms (drug therapy, etiology, pathology)
• Prognosis
• Safety