[Selective internal radiotherapy (SIRT) of liver tumors].

Abstract

METHODICAL INNOVATIONS:

Selective internal radiotherapy (SIRT) is a safe and efficacious, minimally invasive procedure to treat primary and secondary unresectable liver tumors. For hepatocellular carcinoma (HCC), SIRT has proven to be a well-tolerated therapy option even in advanced stages of disease.

STANDARD RADIOLOGICAL METHODS:

In cases of portal vein thrombosis SIRT is the alternative to transarterial chemoembolization (TACE).

PERFORMANCE:

The role of SIRT regarding downstaging and bridging to transplantation is promising and SIRT has also been shown to be highly effective and well-tolerated in metastastic liver disease.

ACHIEVEMENTS:

The results of prospective randomized trials are awaited to prove the efficiency and safety of SIRT described in numerous retrospective and prospective non-randomized studies.

PRACTICAL RECOMMENDATIONS:

The indications are established within the framework of a tumor board.

• Authors: H Duan, M Hoffmann
• Journal: Der Radiologe (Radiologe) Vol. 55 Issue 1 Pg. 48-52 (Jan 2015) ISSN: 1432-2102 [Electronic] Germany
• Vernacular Title: Selektive interne Radiotherapie (SIRT) von Lebertumoren.
• PMID: 25519898 (Publication Type: English Abstract, Journal Article)

Chemical References

• Radioisotopes

Topics

• Brachytherapy (methods)
• Humans
• Liver Neoplasms (diagnosis, radiotherapy)
• Radioisotopes (therapeutic use)
• Radiotherapy, Image-Guided (methods)