Abstract | UNLABELLED: Peritoneal transport status is one of main prognostic factors in patients with end-stage renal disease ( ESRD) treated with chronic peritoneal dialysis (PD). The aim of study was evaluation of influence of peritoneal transport status on selected clinical and biochemical parameters in children with ESRD in first year of PD treatment. MATERIALS AND METHODS: 52 children (mean age 10.3 ± 4.7 years) with preserved residual renal function (RRF) treated with PD were enrolled into the study. In all patients we evaluated in first 12 months of PD treatment: peritoneal equilibration test (PET): D/P (Crea 4h), D/D0 Glu 4h, age, sex, etiology of ESRD, blood pressure, RRF (daily diuresis [mL/kg/24h], residual GFR [mL/min/1.73 m2]), PD parameters, adequacy, rate of PD-related peritonitis, medications, and biochemical parameters. RESULTS: Mean D/P (Crea 4h) was 0.65 ± 0.13, mean D/D0 glu 4h-0.38 ± 0.13. Patients were divided into 2 groups: H/HA (high/high-average) peritoneal permeability--26 (50.0%) and L/LA (low/low-average)--26 (50.0%) children. Patients with H/HA were significantly (P < 0.05): younger, had slower growth rate, higher systolic blood pressure, worse control of arterial hypertension, slower rates of rGFR and twCCr (total weekly clearance of creatinine) decline, higher incidence of peritonitis, lower total protein and albumin; tendency to lower hemoglobin (P = 0.07) compared to patients with L/LA. CONCLUSIONS:
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Authors | Maria Roszkowska-Blaim, Piotr Skrzypczyk |
Journal | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
(Pol Merkur Lekarski)
Vol. 37
Issue 220
Pg. 212-6
(Oct 2014)
ISSN: 1426-9686 [Print] Poland |
Vernacular Title | Znaczenie kliniczne transportu otrzewnowego u dzieci w pierwszym roku leczenia dializa otrzewnowa. |
PMID | 25518575
(Publication Type: Evaluation Study, Journal Article)
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Topics |
- Biological Transport
- Child
- Female
- Humans
- Kidney Failure, Chronic
(metabolism, therapy)
- Male
- Peritoneal Dialysis
- Peritoneum
(metabolism)
- Permeability
- Prognosis
- Retrospective Studies
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